Fig. 4. Assessment of the severity of post-stroke injury. Severity of the post-stroke injury at one-day reperfusion including the degree of recovery during reperfusion was assessed at regular intervals by the modified neurological severity scores (mNSS) test in rats subjected to 2h ischemia followed by seven days reperfusion. Dotted and solid lines represent the data of ischemia-induced animals that were treated immediately after reperfusion with vehicle and exosomes, respectively. Error bars indicate SEM. n=6-9. ^Δp<0.05 vs. 1d reperfusion; ^ΔΔΔp<0.001 vs. 1d reperfusion; ^*p<0.05 vs. vehicle treatment at 3d reperfusion.